Proteins unfold by breaking electrical contacts
Researchers from the University of Amsterdam have discovered that the substance guanidinium chloride unfolds proteins by breaking the electrical contacts that keep a protein molecule together. The discovery is important for a better understanding of the forces that keep a protein in the folded, i.e. healthy state. The article about the discovery will be published online on 2 December and on 8 December in the Journal Angewandte Chemie International Edition.